Endometrial Cancer

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Causes and Risk Factors

The cause of uterine cancer is unknown. Chronic exposure to estrogen (i.e., a female hormone produced by the ovaries) increases the risk for developing the disease and estrogen often affects tumor growth. The following factors increase estrogen exposure:

Early menarche (beginning menstruation before age 12)
Hormone replacement therapy (HRT) with exogenous estrogen (i.e., without progesterone)
Late menopause (after age 52)
Presence of an estrogen-secreting tu...Read the full article